NUR 641 Topic 8 DQ 2

Sample Answer for NUR 641 Topic 8 DQ 2 Included After Question


Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.

A Sample Answer For the Assignment: NUR 641 Topic 8 DQ 2

Title: NUR 641 Topic 8 DQ 2

Type 2 Diabetes Mellitus: Medication

Type 2 Diabetes Mellitus can be managed by the use of oral agents to minimize the adverse effects of the condition. Metformin hydrochloride is the first line drug administered to type 2 diabetes patients. The medication works on a principle of lowering glucose production especially those produced by the pancreas in the liver.  A study by Garber et al. (2018) indicates that Metformin improves the body systems’ sensitivity to insulin. As such, it enhances the metabolism of blood sugar through the improved activity of insulin. The medication is taken 1-3 times daily along with meals and plenty of fluids. In order to enhance the metabolism of the drug, healthy diets and resistive exercise program is recommended. Among adults, 500 mg of Metformin 1 PO BID daily is recommended.  

According to Anagnostou et al. (2016), Metformin medication can be associated with adverse events. Patients on the prescription drug can manifest nausea, vomiting, and diarrhea. The medicine may cause stomach upset and a metallic taste which can go along to alter dietary intake. Patients on the drug may also experience weakness. Type 2 diabetes patients should be discouraged from drinking alcohol as this impairs the metabolism of metformin medication. Metformin impairs the absorption of vitamin B12 and calcium which may necessitate supplementation of the nutrients.

Prescription medications such as digoxin, trimethoprim, and procainamide interact with metformin. Cimetidine, for instance, cause metformin-associated lactic acidosis (MALA) which impairs the bioavailability of metformin. A reduction in the dose of Metformin for patients on Cimetidine therapy is important to ensure effective therapy (Anagnostou et al., 2017). Metformin can be used along with insulin therapy to improve the prognosis of type 2 diabetes mellitus. However, Metformin medication is contraindicated for patients with chronic heart failure, severe renal disease, septicemia, and hypersensitivity. Nonetheless, the drug is not recommended for patients with diabetes ketoacidosis (DKA) and abnormal creatinine clearance.


Anagnostou, E., Aman, M. G., Handen, B. L., Sanders, K. B., Shui, A., Hollway, J. A., … & Butter, E. (2016). Metformin for treatment of overweight induced by atypical antipsychotic medication in young people with autism spectrum disorder: a randomized clinical trial. JAMA Psychiatry73(9), 928-937.

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., … & Garber, J. R. (2018). A consensus statement by the American Association of Clinical Endocrinologists and the American College of Endocrinology on the comprehensive type 2 diabetes management algorithm–2018 executive summary. Endocrine Practice24(1), 91-120.