NUR 641 Topic 5 DQ 2

Sample Answer for NUR 641 Topic 5 DQ 2 Included After Question


Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.

A Sample Answer For the Assignment: NUR 641 Topic 5 DQ 2

Title: NUR 641 Topic 5 DQ 2

One of the drugs used in the treatment of varicose vein is Polidocanol; though, there are other techniques used as well including the surgical option (McCance & Huether, 2014). The Polidocanol drug induces the sclerosant effect by influencing the concentration-dependent cell differential cell injury. The process activates the cellular calcium signaling and the nitric oxide pathway which then administers the sclerosant and causing cell death. The timing of the endothelial cell death depends on the sclerosant concentration (Star, Connor, & Parsi, 2018). The drug has been proven to be effective in the treatment of varicose vein; though, there are associated side effects such as chest tightness and impaired vision. Additionally, patients are likely to experience mild numbness, dizziness and increase the growth of hair on the treated legs.

The recommended amount of the drug varies depending on the size of the varicose vein. Usually, 0.3ML of 1% solution is used per injection. The drug may interact with other medications in the body. Furthermore, it can pass through the milk and thus non-recommended for breastfeeding mothers. The sclerosant effect causes the veins to scar and thus force the blood to reroute through the healthier veins (Gao, Zhang, Li, & Shi, 2016). Additionally, the collapsed veins are reabsorbed into the local tissues and finally fade. The treatment outcomes may take time to be seen because the fading tend to take time. Furthermore, the process alleviates the symptoms associated with varicose vein such as the night cramps, aching and swelling among others. Finally, the targeted outcome in the treatment of varicose vein is to restore the integrity of the veins and valves and prevent reflux. The drug is effective in alleviating the varicose vein symptoms and thus recommended and most commonly used.


Gao, Z., Zhang, Y., Li, W., & Shi, C. (2018). Effectiveness and safety of polidocanol for the treatment of hemangiomas and vascular malformations: A meta‐analysis. Dermatologic Therapy, 31(1), 1.

McCance, K. L., & Huether, S. E. (2014). Pathophysiology E-Book: The Biologic Basis for Disease in Adults and Children. St. Louis, MO: Elsevier Health Sciences.

Star, P., Connor, D. E., & Parsi, K. (2018). Novel developments in foam sclerotherapy: Focus on Varithena® (polidocanol endovenous microfoam) in the management of varicose veins. Phlebology, 33(3), 150–162.