NUR 641 Topic 5 DQ 1

Sample Answer for NUR 641 Topic 5 DQ 1 Included After Question


Choose a medical condition from the cardiovascular system and lymphatic system and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.

A Sample Answer For the Assignment: NUR 641 Topic 5 DQ 1

Title: NUR 641 Topic 5 DQ 1

Varicose vein is a condition that results from venous hypertension and results in incompetence in the major communications between the deep and superficial veins of the lower extremities. The condition results from the disruptions in the normal venous architecture due to the remodeling of the extracellular matrix (McCance & Huether, 2014). The remodeling emerges as a response to the increased venous distention and disruptions in the hemodynamic shear. In as much as genetic factors and growth factors have been associated with the development of a varicose vein, its pathogenesis is linked to the remodeling of the extracellular matrix. The main etiology of the condition remains unknown with various patients requiring mapping to determine the source and drainage in the area of reflux.

Veins have one-way valves that prevent reflux. When veins become enlarged due to the remodeling, knots are developed and can be seen near the surface of the skin. Most of the knots are formed at the saphenofemoral junction and the saphenopopliteal junction (Ortega et al., 2018).  The superficial veins are vulnerable to the remodeling because they cannot withstand much pressure as evident in the case of the deep veins.

The varicose vein can results in other complications due to the venous insufficiency including chronic ulceration. Additionally, they are likely to develop stigma due to the visible knots and edema at various points in the lower extremities. Therefore, education for such patients should focus on the importance of adhering to the medical prescriptions accordingly. Furthermore, the patients should be educated on the importance of being positive about the condition to avoid psychological distress and stigmatization (Mishra & Singh, 2016). Furthermore, the patients ought to be informed about the importance of engaging in regular exercise and avoid standing for long hours.


McCance, K. L., & Huether, S. E. (2014). Pathophysiology E-Book: The Biologic Basis for Disease in Adults and Children. St. Louis, MO: Elsevier Health Sciences.

Mishra, S., Ali, I., & Singh, G. (2016). A study of epidemiological factors and clinical profile of primary varicose veins. Medical Journal of Dr. D.Y. Patil University, 9(5), 617–621.

Ortega, M. A., Romero, B., Asúnsolo, Á., Sainz, F., Martinez-Vivero, C., Álvarez-Mon, M., … García-Honduvilla, N. (2018). Behavior of Smooth Muscle Cells under Hypoxic Conditions: Possible Implications on the Varicose Vein Endothelium. BioMed Research International, 1–9.