NUR 631 Topic 1 DQ 2

Sample Answer for NUR 631 Topic 1 DQ 2 Included After Question

Use the “Discussion Forum Sample” to answer two of the following questions.

  1. What is the difference between epigenetics and genetics?
  2. In nurse practitioner clinical practice, how would one apply the principles of epigenetics when determining the plan of care for a patient?
  3. What is the difference between hyperplasia, dysplasia, and metaplasia in relation to epigenetic disorders?

A Sample Answer For the Assignment: NUR 631 Topic 1 DQ 2

Title: NUR 631 Topic 1 DQ 2

The master plan in life program is DNA and its ability to reproduce a diversity of physical and behavioral traits. In addition, when a disease is found by alterations in the cellular genetic control of the DNA, then the change and sequence of the Nucleotides give birth to changes in cellular physiology and gene mapping that increase curiosity to the now study of Genetics

In contrast, to Genetics and specific rules the Epigenetic remains a topic of discussion with the scientific community. The term is used for modifications that are not encoded in the nucleotide sequence but are transmitted when a somatic cell divides when gametes are produced in germline inheritance (McCane & Huerther, 2018). The definition of Epigenetic is referred to modulation on how a given set of genomic information gives rise to phenotype. Moreover, including chemical modifications to DNA by histones, production of small regulatory RNA molecules and regulation epigenetic processes at transcription or translation (McCane & Huether, 2018).

The clinician needs to be clear and prudent with information that are explained in terms of how this condition is not at fault on family but on genetic disorder that research is continuation of screening is ongoing. Provide information on counseling and child protection.

Reference

Capriotti, T. (20AD, April 2). Davis Advantage for pathophysiology: Introductory concepts and clinical perspectives. Google Books. https://books.google.com/books/about/Davis_Advantage_for_Pathophysiology.html?id=g7gBywEACAAJ

McCance, K. L., & Huether, S. E. (2018). Pathophysiology (8th ed.). Elsevier Health Sciences.

A Sample Answer 2 For the Assignment: NUR 631 Topic 1 DQ 2

Title: NUR 631 Topic 1 DQ 2

Epigenetics involves the relationship between our gene activity and our environment. In epigenetics, gene activity is influenced but the gene sequence is unchanged. These changes are often reversible (Pajouhesh, 2021). 

Genetics is the study of genes and heredity. The study of genetics focuses on how certain traits are passed on from parents to their offspring. These traits are the result of changes in the DNA sequence (NIH, 2022).

The difference between epigenetics and genetics is genetics studies the way genetic changes alter the DNA sequence and epigenetics studies the effects of environment and behaviors on the way the genes are expressed (CDC, 2022).

Epigenetics can be used to evaluate how external factors affect our genes and how our genotype interacts and is influenced by our environment. By understanding what influence certain environmental and lifestyle factors play in our genetic activity and how they lead to disease processes we can counsel our patients on modifications they can make to limit the negative effects and optimize the positive. For example, exercise has been known to play a large part in health and well-being. Lack of exercise has also been linked with multiple chronic disease.

Epigenetic changes have been shown by research to occur in response to resistance and aerobic exercise. These changes have been shown to occur in skeletal, blood, adipose, and brain tissue. Exercise alters molecular processes in our tissues that cause them to change and adapt leading to the positive effects of exercise (Thunders, 2015). Epigenetics will play a vital role in increasing our awareness of how our interaction with our physical space influences our well-being and emphasizes the importance of holistic and preventative care to reduce the negative impacts of epigenetic changes (Pajouhesh, 2021). 

Pajouhesh, P. (2021). Epigenetics as a tool for personalized and targeted care. UC Davis. Retrieved on May 08, 2023, from https://aggietranscript.ucdavis.edu/epigenetics-as-a-tool-for-personalized-and-targeted-care/

National Institute of Health. (2022). Genetics. Retrieved on May 08, 2023, from  https://nigms.nih.gov/education/fact-sheets/Pages/genetics.aspx

Centers for Disease Control. (2022). Genomics & Precision Health. Retrieved on May 08, 2023, from https://www.cdc.gov/genomics/disease/epigenetics.htm#:~:text=While%20genetic%20changes%20can%20alter,and%20your%20behaviors%20and%20environment. Thunders, M. (2015). Epigenetics: Its understanding is crucial to a sustainable healthcare system. Healthcare, 3(2), 194-204. https://doi.org/10.3390/healthcare3020194