NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research

Sample Answer for NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research Included After Question

Topic 3 DQ 1

Assessment Description

Discuss the ethical guidelines that would need to be implemented when conducting translational research.
What are the ethical and legal considerations related to translating research into practice? Discuss what steps
you would take as a member of a translational research team in order to establish ethical guidelines for
conducting translational research.

A Sample Answer For the Assignment: NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research

Title: NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research

Practicing ethical guidelines when conducting and reporting research studies, whether translational or not, is essential to establishing research validity. Researchers must adhere to ethical guidelines issued by regulatory bodies and committees to ascertain the safety of participants. Translational research is unique since it focuses on transfer of scientific knowledge into clinical practice and mainly involves and targets human subjects (Riva & Petrini, 2019). Therefore, ethical and legal guidelines are imperatives for those conducting these studies. The three main principles include respect of persons, beneficence and justice. It is essential to comply with the ethical principles to protect the dignity, rights, and welfare of the research subjects.

The researchers must also consider compliance to the legal provisions as stipulated by laws like HIPAA and HITECH on aspects like privacy, confidentiality, and ensuring that participants are not minors. Legal considerations also require the attainment of informed consent from the participants. The implication is that participants should know the risks and benefits involved in a study for them to make informed decisions (Daverio, 2019). The researchers must provide all the necessary information, including the side effects of a study for potential subjects to make informed decisions and offer their consent. Minors do not have autonomy and individuals with disabilities should also be considered as vulnerable.  

Members of translational research teams should ensure that they adhere to the existing ethical guidelines and legal requirements when carrying out studies. These entail having approval from Institutional Revie Boards, using biomedical principles and ascertaining that there is confidentiality, privacy through applying a risk-benefit approach (Riva & Petrini, 2019). Ethical considerations and legal requirements will ensure the validity and reliability of research and its findings.

References

Daverio, M. (2019). Informed Consent in Translational/Clinical Research. Ethical Issues

According to International Guidelines. BioLaw Journal-Rivista di BioDiritto, 16(1S), 123-138.

Riva, L. & Petrini, C. (2019). A few ethical issues in translational research for gene and cell

therapy. Journal of Translational Medicine, 17(395). DOI: https://doi.org/10.1186/s12967-019-02154-5

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A Sample Answer 2 For the Assignment: NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research

Title: NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research

Translation science is also referred as the implementation science and it involves testing an implementation intervention to enhance the uptake and utilization of the evidence in improving a patient’s outcomes. Evidence-based studies are defined as a translational research because they constitute the frameworks used in the development of implementation plan with the aim of improving the quality of healthcare delivery (Titler, 2014).

NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research
NUR 550 Discuss the ethical guidelines that would need to be implemented when conducting translational research

The scientific methodologies adopted herein investigate the best implementation measures to use in the evidence-based practices and uncover the approaches through which they operate. Developments in the translational research are used in the expedition and sustenance of the successful integration of the evidence-based practices in improving the quality of healthcare delivery. Translational science grows at a higher rate in the investigation field with most of the healthcare practices being based on the evidence-based interventions, hence the two are strongly correlated.

The backbone of the translational science entails employing the implementation measures that utilize evidence-based practices in improving the quality of healthcare delivery to the patients (Jordan, Lockwood, Munn & Aromataris, 2019). Therefore, the definition of the evidence-based practice as a translational research is based on the fact that EBPs act as guidelines in the formulation of recommendations used to improve the quality of healthcare practices.

One of the population health issues affecting majority of people in the current era is high incidence of childhood obesity. The prevalence of obesity among children continues to raise serious global threats; therefore, there is need to develop appropriate and prompt intervention measures to address it. Indeed, according to statistics on the matter, the rise in the rates of global childhood obesity has coincided with increase in childhood mortality rates in the world. Using evidence-based practices and translation research approach, the issue can be addressed by exploring unique factors contributing to the existence of the issue in the society and developing recommendations based on the results.

Furthermore, the recommendations are used to implement programs that aim at improving public health by reducing the incidences of childhood obesity. The recommendations are based on data and facts obtained from research, which have proven their usefulness in managing the condition (Curtis, Fry, Shaban & Considine, 2017). Identifying that the needs of patients vary from one person to another, the implementation design should be customized within the community or social setting. Indeed, creating an intervention based on uniqueness on a community or tailoring it to the realities of a community influences its effectiveness.

Recommendations developed must be based on valid research findings. The research findings ought to be focused on assessing the sustainability of the intervention effects and address any possible evidence gaps. Undertaking that will ensure applicability of the elected interventions as supported by studies on the same.  Moreover, accelerating the discovery of necessary evidence-based programs and policies such as educating the public on causes and measures to prevent childhood obesity assume a great significance. The adoption of such recommendations ensures that public health matters become greatly improved in the world.

Therefore, in order to complete an EBP project, proper approaches must be used in the terms of research design, sample population identification and testing the validity and credibility of study findings. As illustrated in the translational research, the research process must provide reliable findings that can be applied practically to address the community needs.

References

Curtis, K., Fry, M., Shaban, R. Z., & Considine, J. (2017). Translating research findings to clinical nursing practice. Journal of clinical nursing26(5-6), 862-872.

Jordan, Z., Lockwood, C., Munn, Z., & Aromataris, E. (2019). The updated Joanna Briggs Institute Model of Evidence-Based Healthcare. International journal of evidence-based healthcare17(1), 58-71.

Titler, M. G. (2014). Overview of evidence-based practice and translation science. Nursing Clinics49(3), 269-274.

APRN’s are initiating change projects more frequently in today’s healthcare system. Based on this model, organizational change may be managed by nurse managers, nurse leaders, and/or nurse educators overseeing staff on a designated unit or department. For change to be effective, nurse leaders need to communicate and collaborate with their team. To implement change, many different stakeholders can be involved in this process as well. When preparing to initiate a change project, “a change implementation should not be decided on before the stakeholders are analyzed. However, once the implementation is decided on, new stakeholders may be identified and added to the analysis,” (DeNisco, 2024). Stakeholders will play a role in organizational change from an operational and management standpoint, financial contributions, and assisting to implement a change. 

American Nurses Association (ANA). (2018). Integrating Lewin’s Theory with Lean’s System Approach for Change. The Online Journal of Issues in Nursing . https://ojin.nursingworld.org/table-of-contents/volume-21-2016/number-2-may-2016/-integrating-lewins-theory-with-leans-system-approach/

DeNisco, S. M. (2024). Advanced practice nursing: Essential knowledge for the profession (5th ed.). Jones & Bartlett Learning.