NRS 445 Topic 4 DQ 1

Sample Answer for NRS 445 Topic 4 DQ 1 Included After Question

Assessment Description

Statistical significance refers to the likelihood that the results of a study are not due to chance, while clinical significance refers to the practical importance of the results in terms of their impact on patient care. In other words, statistical significance is a measure of the strength of the evidence, while clinical significance is a measure of the relevance of the evidence to real-world situations.

Using a quantitative research article from one of the previous topics, analyze the p-value. What is it? Is it statistically significant? If your p-value is not statistically significant, what is the clinical significance? Generalizability of research depends on a variety of factors. List three factors of generalizability, and discuss whether this research article is generalizable to the nursing problem you are researching.

Initial discussion question posts should be a minimum of 200 words and include at least two references cited using APA format. Responses to peers or faculty should be 100-150 words and include one reference. Refer to “RN-BSN Discussion Question Rubric” and “RN-BSN Participation Rubric,” located in Class Resources, to understand the expectations for initial discussion question posts and participation posts, respectively.

A Sample Answer For the Assignment: NRS 445 Topic 4 DQ 1

Title: NRS 445 Topic 4 DQ 1

Interpretation of research findings is important in determining how the findings can be used in clinical settings to improve patient outcomes. Therefore, for a long time, statistical significance and clinical significance are two terms that have been used to measure the strength of the evidence presented and the relevance of the evidence to real-world situations respectively.

Therefore, as part of evidence appraisal and measurement of the evidence strength, it is important to explore various aspects, such as the p-value, which offers an insight into statistical significance. For the purposes of this discussion, the chosen article is an article authored by Kai-Larsen et al. (2021). The purpose of this research was to explore the efficacy of the noble metal alloy-coated BIP Foley Catheter in preventing the incidence of CAUTI.


NRS 445 Topic 4 DQ 2

NRS 445 Topic 5 DQ 1

NRS 445 Topic 5 DQ 2

NRS 445 Final Draft – Research Critiques and Evidence-Based Practice Proposal

The analysis of the data obtained included, among other things, determining the statistical significance. Therefore, the use of Foley catheters led to a statistically significant reduction in CAUTI incidences (p<0.001). Therefore, the p-value obtained is an indication that the change observed in the CAUTI incidences was not by chance but was due to the use of the noble metal alloy-coated BIP Foley Catheter (Rose-Nussbaumer, 2021). Another important aspect of reported findings in a research article is generalizability.

Therefore, it is also important to explore whether the findings are generalizable or not. The generalizability of research depends on various factors. One of the factors is the research method and design used. For instance, research efforts that used a bigger sample in the cases of randomized controlled trials will be more generalizable than those that use a smaller and homogeneous sample (Degtiar & Rose, 2023). The other factor is external validity and context. The next factor is the population of focus; a sample that represents a larger population is likely to be more generalizable. The findings in the article of focus are generalizable since the population was sufficient as the total number of participants was 1000. In addition, the research was also conducted across six different hospitals.


Degtiar, I., & Rose, S. (2023). A review of generalizability and transportability. Annual Review of Statistics and Its Application10, 501-524.

Kai-Larsen, Y., Grass, S., Mody, B., Upadhyay, S., Trivedi, H. L., Pal, D. K., … & Singh, S. K. (2021). Foley catheter with noble metal alloy coating for preventing catheter-associated urinary tract infections: a large, multi-center clinical trial. Antimicrobial Resistance & Infection Control10, 1–10. 10.1186/s13756-021-00907-w

Rose-Nussbaumer, J. (2021). Statistical Significance vs Clinical Significance—That Is the Question. JAMA Ophthalmology139(11), 1235-1235. Doi: 10.1001/jamaophthalmol.2021.4139.